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Last night I was watching Mystery Diagnosis on TV and saw many similarities between my daughter and Gabby. My daughter has been having recurrent high fevers since she was 3mths old-she is 4 yrs old now. Just about every month she is sick. She will tell me that she dosn't feel good and the her belly hurts. She will sleep and be lethargic. Motrin will bring the fever down. She has been hospitalized twice. She will have blood in her urine, ketones in her urine and electrolyte inbalance during her fever episodes. We have been to many specialist, and have had many test done. She has also had dental surgery due to lack of enamal on her teeth. We were told that this was most likely caused be her fevers. No one knows why she gets these fevers. I saw the show last night and decided to look up APS on line and found this website. If you have any idea what may be causing these fevers or know what test I should ask to be performed that would be great. Thanks, a concerned mom

Response

Posted by dr at June 27, 2008 11:10 AM
You might look up periodic relapsing fevers and Mediterranean fevers to help resolve the diagnosis. However the lack of dental enamel does raise the remote possibility of APS-1. Have any of the blood calcium values been low? What electrolyte disturbances have occurred? A raised potassium especially with low sodium level could mean adrenal deficiency. If so antibodies to 21-hydroylase should be sent. At this age, celiac disease should also be considered (transglutaminase antibody test).
Kind regards,
Noel Maclaren MD

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